Látták: Átírás 1 27 th Congress of the Federation of the International Danube Symposia on Diabetes Mellitus PROGRAMME Zentraleuropäische diabetesgesellschaft, June 2 Wörwag Neuropathy Specialist Thiogamma alpha-lipoic acid mg Thiogamma oral Active ingredient: alpha-lipoic acid mg, Film-coated tablet Therapeutic Indication: Sensory disturbances in cases of diabetic polyneuropathy Dosage: Diabetic gastroparesis diet handout and Daily Doses: In the case of sensory disturbances associated with diabetic polyneuropathy, the following daily dose is recommended for adults: The daily dose is 1 Thiogamma oral film-coated tablet equivalent to mg of alpha-lipoic acidwhich is taken approximately 30 minutes before the first meal.
In cases of severe klinikák típus diabetes disturbances, infusion therapy with alpha-lipoic acid can be carried out initially. Properties: Alpha-Lipoic acid is diabetic gastroparesis diet handout vitamin-like, but endogenously formed diabetic gastroparesis diet handout with a coenzyme function in the oxidative decarboxylation of alpha-keto acids. Contraindications: Thiogamma oral is totally contraindicated in patients with known hypersensitivity to alpha-lipoic acid or any of the other constituents of Thiogamma oral.
Note: Children and adolescents should not be treated with Thiogamma oral, as there is no clinical experience of this age group. Interactions: Loss of efficacy of cisplatin during simultaneous treatment with Thiogamma oral.
For this reason, close monitoring of blood sugar levels is indicated, particularly during the initial phase of alpha-lipoic acid therapy. In order to avoid the symptoms of hypoglycaemia it may prove necessary in individual cases to reduce the diabetes rét dose or the dose of the oral anti-diabetic.
The regular consumption of alcohol represents a significant risk factor for the development and progression of neuropathic clinical pictures and may therefore prevent the success of treatment with Thiogamma oral. Patients with diabetic polyneuropathy are therefore recommended as a matter of principle to avoid the consumption of alcohol as much as possible.
Undesirable effects: Very rare: Change in taste sensations, nausea, vomiting, gastrointestinal pain and diarrhoea, Allergic reactions such as skin rash, hives urticaria and itching, Because of improved glucose utilization, a fall in blood sugar levels may occur. Symptoms similar to those of hypoglycaemia have been described such as vertigo, diaphoresis, headache and altered visual perception.
Date of Revision of the Text: September Prescription Status: Only available from pharmacists Please refer to the complete summary of product characteristics for your country as variations may exist.
The right partnership may get you there. The addition of BYETTA is now approved for patients with type 2 diabetes inadequately controlled on an existing regimen of basal insulin.
BYETTA 5μg and 10μg solution for injection, prefilled pen Abbreviated Summary of product characteristics Each dose contains 5 or 10 micrograms μg exenatide in 20 or 40 microlitres μl respectively0.
Each pre-filled pen contains 60 doses of sterile preserved solution.
Gastroparesis (Stomach Paralysis) - Causes and Risk Factors, Signs \u0026 Symptoms, Diagnosis, Treatment
Therapeutic indications: BYETTA is indicated for treatment of type 2 diabetes mellitus in combination with metformin, sulphonylureas, thiazolidinediones, metformin and a sulphonylurea, metformin and a thiazolidinedione in adults who have not achieved adequate glycaemic control on maximally tolerated doses of these oral therapies.
Posology and method of administration: BYETTA therapy should be initiated at 5 μg exenatide per dose administered twice daily BID for at least one month in order to improve tolerability. The dose of exenatide can then be increased to 10 μg BID to further improve glycaemic control. Doses higher than 10 μg BID are not recommended.
BYETTA can be administered at any time within the minute period before the morning and evening meal or two main meals of the day, approximately 6 hours or more apart.
If an injection is missed, the treatment should be continued with the next scheduled dose. When BYETTA is added to sulphonylurea therapy, a reduction in the dose of sulphonylurea should be considered to reduce the risk of hypoglycaemia.
Ily mdon rhet el, hogy az inzulin aktulis vrszintje legjobban hasonltson az egszsges hasnylmirigy inzulin-elvlasztsi dinamikjhoz, minimlisra cskkentve a hypoglykaemia veszlyt. Az intenzv inzulinkezels fogalma Az intenzv inzulinkezels olyan tbbkomponens kezelsi rendszer, amelynek clja az egyes tkezsek, valamint az tkezs-mentes napszakok idelis inzulinszksgletnek biztostsa, napjban tbbszr adott inzulin segtsgvel.
In patients at increased risk of hypoglycaemia consider reducing the dose of basal insulin. However, blood glucose self-monitoring may become necessary to adjust the dose of sulphonylureas or the dose of basal insulin.
The safety and effectiveness of exenatide have not been established in patients under 18 years of age. Each dose should be administered as a subcutaneous injection in the thigh, abdomen, or upper arm. Contraindications: Hypersensitivity to the active substance or to any of the excipients.
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Special warnings and precautions for use: BYETTA should not be used in patients with type 1 diabetes mellitus or for the treatment of diabetic ketoacidosis. The concurrent use of BYETTA with D-phenylalanine derivatives meglitinidesalpha-glucosidase inhibitors, dipeptidyl peptidase-4 inhibitors or other GLP-1 receptor agonists has not been studied and cannot be recommended.
This medicinal product contains metacresol, which may cause allergic reactions. Interaction with other medicinal products: Gastroresistant formulations containing substances sensitive for degradation in the stomach, such as proton pump inhibitors, should be taken at least 1 hour before or more than 4 hours after BYETTA injection.
Fertility pregnancy and lactation: If a patient wishes to become pregnant, or pregnancy occurs, treatment with BYETTA should be discontinued. Frequency not known: INR increased with concomitant warfarin, some reports associated with bleeding.
Patients who develop antibodies to exenatide tend to have more injection site reactions for example: redness of skin and itchingbut otherwise similar rates and types of adverse events as those with no antiexenatide antibodies.
Pack size of 1 pen, injection needles are not included. For more information please read the Summary of Product Characteristic. Use of twice-daily exenatide in basal insulin-treated patients with type 2 diabetes: a randomized, controlled trial.
Ann Intern Med. Ferranini et al.
Diabetes, Obesity and Metabolism, 11,Bolli G. Diabetes, Obesity and Metabolism,Rosenstock J. Diabetes CareBosi et al. Diabetes Care ; Eü pont.